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Development of Multi-residual Analytical Methods for Pharmaceuticals, Nitrosamines, Hormones and POPs in Water
International Collaboration of
WARC (Republic of Korea), TZW (Germany), NIAES (Japan), OCWD (USA)

Cover of the Report (Volume I)
International Collaborative Research Reports (Volume 1)


This achievement is based upon a cooperative research agreement between Orange County Water District (OCWD) of US and Water Analysis and Research Center (WARC) of K-WATER of the Republic of Korea and Technology Center for Water (TZW) of German and the National Institute for Agro-Environmental Science (NIAES) of Japan.

Research Goals

To minimize efforts of monitoring, risk assessment and policy making for emerging contaminants such as pharmaceuticals, hormones, disinfection byproducts, perfluorinated compounds and POPs etc., it is required to develop the multi-residual analytical methods of these compounds at aquatic environment. Therefore, we will develop analytical methods using new high-tech instruments including MS/MS or high resolution technique for wide range of water samples and also monitor to estimate their risks.

Our research goals are;

Subject compounds in each institutions

K-water (Republic of Korea)

Animal antibiotics by LC/MS/MS
Sulfamethazine, Sulfamerazine, Sulfaquinoxaline, Sulfamonomethoine, Sulfadimethoxine, Sulfamethoxazole, Sulfachloropyridazine, Sulfathiazole, Sulfameter, Acetaminophene, Carbamazepine, Diltiazem, Trimethoprime, Caffeine, 1,7-dimethylxanthibne, Diclofenac


Nitorsamines by GC/MS/MS/CI
nitrosodimethylamine (NDMA), nitrosomethylethylamine (NMEA), nitrosodiethyamine (NDEA), nitrosopropylamine(NDPA), nitrosopyrrolidine (NPYR), nitrosopiperidine(NPIP), niitrosodibutylamine (NDBA), nitrosomorpholine(NMOR)
Hormone/Steroids by LC/MS/MS
Estrone, Epitestosterone, Testosterone, Estriol, 17a-Estradiol, 17b-Estradiol, 17a-ethynylestradiol, Progesterone, Diethystibestrol

NIAES (Japan)

POPs and candidates by GC/HRMS
Aldrin, Dieldrin, Endrin, Chlordane, Heptachlor, Heptachor epoxide, HCB, Mirex, HCHs (a,b,g,d), (o)p,p'-DDT, (o)p,p'-DDE, (o)p,p'-DDD, transnonachlor, oxy-CHL

TZW (Germany)

1. Human phamaceuticals by LC/MS/MS
1.1 requested compounds by Kwater
Amoxicillin, Cefaclor, Roxithoromycin, Cephradine, Cefatrizine, Cefadroxil, Aztreonam, Ceftazidime, Rifampicin, Ribostamycin, Ceftezole
1.2 suggested comounds by TZW
Salbutamol, Clenbuternol, Terbutaline, Diazepam, Pentoxifyline, Diclofenac, Ibuprofen, Ketoprofen, Indomethacin, Naproxan, Fenoprofen, Phenazone, Dimethylaminophenazone, Propyphenazone, Carbamazepine, Iopamidol, Iopromide, Iomeprol, Amidotrizoic acid, Clofibrinc acid, Bezafibrate, Fenofibrate, Fenofibric acid, Gemfibrozil, Simvastatin, Metoprolol, Propranolol, Atenolol, Bisoprolol, Sotalol, Pindolol, Betaxolol, Ifosfamide, Cyclophosphamide
2. Perfluorinated compounds by LC/MS/MS (TZW suggestion is matched to the Kwater request)

International Collaboration on Multi-residual Analysis for Water Environment: Agreement Ceremony,
17 April, 2007, K-water, Korea

Photo-1 (Agreement Ceremony) Photo-2 (Agreement Ceremony)

International Seminar on Multi-residual Analysis for Water Environment
29 August 2008, K-water, Korea

Photo-3 (International Seminar 2008) Photo-4 (International Seminar 2008) Photo-5 (International Seminar 2008)

Research Reports (Volume 1)

Reports on The International Collaborative Research:
Development of Multi-residual Analytical Methods for Pharmaceuticals, Perfluorinated Compounds, Nitrosamines, Hormones and POPs in Water (Volume I).
(Edit. Jaewon Choi)
Korea Institute of Water and Environment (2008)


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