Agrogenomics Research Center

Biomolecular Research Unit


Structure-based drug design and protein modification

 Organisms perform life activities on the basis of sophisticated biomolecular systems composed of proteins, nucleic acids, sugars, lipids and other molecules. These biomolecules exert their functions through interactions with other biomolecules, which are modulated primarily by three-dimensional structures of the interacting molecules. Hence, understanding of biomolecular functions and life systems requires a detailed knowledge of molecular structures and interaction mechanisms. At the Biomolecular Research Unit, we analyze structures and functions of biomolecules involved in important life phenomena related to agriculture and thereby discover substances and strategies that can control functional mechanisms of these biomolecules. We also perform proteome analysis to understand the temporal and spatial behaviors of biomolecular systems.

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    Structures and functions of biomolecules are investigated using various analytical methods.