Genetically Modified Organism Research Center

Transgenic Pig Research Unit

Development of transgenic pig by advanced gene manipulation for practical use

 Swine are markedly similar to humans regarding anatomy, physiology and genetics and offer substantial advantages as a human model. It is very important to establish highly benefi cial human models, such as a disease model as a primary objective, to increase the utilization of pigs in biomedical research. The fi nal goal of our unit is to develop advanced technology for production of transgenic pigs via genetic engineering combined with cloning for practical applications. Severe combined immunodefi ciency (SCID) pigs for human cell transplantation, human lifestyle-related disease models, and human cancer models are our objectives.

Production of transgenic pigs by nuclear transfer