Livestocks play an important role in our lives. Animal products such as milk, meat, and eggs supply the proteins we need to stay healthy and build strong bodies. Safe, high quality animal products are produced from healthy livestocks. Animals also contribute to the advancement of biotechnology and life sciences. The preservation of animal health through the implementation of preventive measures to contain various diseases is an important goal. The National Institute of Animal Health (NIAH) covers basic research to diagnosis and contributes to support animal health.
The National Institute of Animal Health, NARO (NIAH) performed experimental infection with classical swine fever virus (JPN/1/2018 strain) which was isolated from Gifu prefecture, Japan for the first time in 26 years. It was revealed that JPN/1/2018 strain causes high fever and leukopenia in pigs, this strain is less pathogenic than the highly pathogenic strain. Moreover, it was also found that it spreads to the cohabiting pigs. Virus was detected from blood, saliva, fecal and nasal discharge of infected pigs at least for 2 weeks. And the antibody was detected 2 weeks later after the co-rearing or virus inoculation.Read more
The National Institute of Animal Health, NARO (NIAH) performed genetic sequence analysis of the causative virus of classical swine fever which was isolated from an outbreak in Gifu Prefecture, Japan for the first time in 26 years. The virus isolated from infected pigs in Gifu Prefecture on September 9, 2018 belongs to the subgenotype 2.1 group based on the sequence of the classical swine fever viruses registered in the international database of nucleotide sequences.Read more
The 2nd Scientific Meeting on Foot-and-Mouth Disease (FMD) between the Regional Reference Laboratory for Foot-and-Mouth Disease in Southeast Asia (RRL) based in Thailand and the Exotic Disease Research Station, National Institute of Animal Health, NARO (NIAH) was held on Feb 15-16, 2018 in Kodaira, Tokyo, Japan. The RRL and NIAH/NARO have more than 50 years history of research and technology exchange related to animal health and the MOU for joint research collaboration was concluded in 2012. The meeting focused on the current status of FMD research in Japan and Southeast Asia including presentations from the Center for Animal Disease Control (CADIC) of Miyazaki University, and the Animal Quarantine Service of the Ministry of Agriculture, Forestry and Fisheries (MAFF). The next scientific meeting will be held at RRL in Pakchong, Thailand in 2019.
The National Institute of Animal Health, NARO (NIAH) performed the full-genome sequence analysis of highly pathogenic avian influenza virus (HPAIV) which isolated from an outbreak in Kagawa Prefecture in January 2018. It was revealed that this virus underwent a gene reassortment between an H5N8 virus that was epidemic in Europe last year and an HxN6 virus in wild birds. Intervention against the intrusion of HPAIVs which are carried by wild birds into poultry farms is needed to prevent HPAI in poultry.Read more.
In the National Institute of Animal Health NARO, we identified the subtypes of highly pathogenic avian influenza (HPAI) virus which isolated from Aomori and Niigata cases on November 28. We performed the whole genome analysis to estimate the origin and pathogenicity of the virus at the gene level. We identified HPAI causative virus (Aomori strain, Niigata strain) which isolated in Aomori and Niigata Prefectures as H5N6 subtype highly pathogenic avian influenza virus (HPAIV). Using the next-generation sequencer, we determined the nucleotide sequences of 99.5% (Aomori strain) and 100% (Niigata strain) of each virus genome. The nucleotide sequences of the two viruses have mutual homology of 99.2% or more in all of the 8 RNA segments each other. In addition, both viruses showed 99.3% or more homology with the virus which is isolated from the water of the nesting place of hooded crane of Izumi City, Kagoshima.Read more.
The National Institute of Animal Health (NIAH) provides technical support in the fight against foot-and-mouth disease (FMD) and other transboundary animal diseases (TADs) for Mongolia through the World Organization for Animal Health (OIE). FMD is one of the most feared livestock diseases: it is highly infectious and a serious threat to the economic value of livestock. The NIAH, which is the only institution providing definite diagnosis of FMD in Japan, has been designated as a collaborating center of the OIE. The NIAH decided to provide technical support to the State Central Veterinary Laboratory (SCVL) in Mongolia to improve the diagnostic techniques for FMD and other TADs through the twinning project, which has been approved by the OIE.