We have analyzed virulence factors of E. rhusiopathiae using transposon mutagenesis with Tn916. The results obtained have demonstrated that E. rhusiopathiae may have a capsule and virulence of the organism is a associated, in part, with resistance to phagocytosis by polymorphonuclear leukocytes.
(Lab. of Physiological Active Substances Research, Biological Products Research Division)
