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Distinct Human and Mouse Membrane Trafficking Systems for Sweet Taste Receptors T1r2 and T1r3

NARO, RIKEN and Okayama University found out that human T1R3 surface expression was only observed when human T1R3 was coexpressed with human T1R2, whereas mouse T1r3 was expressed without mouse T1r2 expression. These features are indicating that human T1R2 and T1R3 are likely to have a novel membrane trafficking system. Published in PLOS ONE on July 16, 2014 online.