Division of Animal Sciences

Animal Immune and Cell Biology Research Unit


2013-2015   2011-2012

  1. Aoki S, Takezawa T, Ikeda S, Narisawa Y, Oshikata-Miyazaki A, Miyauchi S, Hirayama H, Sawaguchi T, Chimuro T, Toda S (2015) A new cell-free bandage-type artificial skin for cutaneous wounds Wound Repair and Regeneration (Published Online):Accepted Article 10.1111/wrr.12321
  2. Bergman I.M, Okumura N, Uenishi H, Hammer S.E, Knoll A, Edfors I, Juul-Madsen H.R (2015) Wild boars from Sweden, Austria, the Czech Republic and Japan possess intact mannose-binding lectin 2 (MBL2) genes International Journal of Immunogenetics 42(3):204-207
  3. Chae J.J, McIntosh Ambrose W, Espinoza F.A, Mulreany D.G, Ng S, Takezawa T, Trexler M.M, Schein O.D, Chuck R.S, Elisseeff J.H (2015) Regeneration of corneal epithelium utilizing a collagen vitrigel membrane in rabbit models for corneal stromal wound and limbal stem cell deficiency Acta Ophthalmologica 93(1):e57-e66
  4. Escalona Z, Álvarez B, Uenishi H, Toki D, Yuste M, Revilla C, Gómez del Moral M, Alonso F, Ezquerra A, Domínguez J (2015) Molecular characterization of porcine Siglec-10 and analysis of its expression in blood and tissues Developmental & Comparative Immunology 48(1):116-123
  5. Sakuma C, Sato M, Oshima T, Takenouchi T, Chiba J, Kitani H (2015) Anti-WASP intrabodies inhibit inflammatory responses induced by Toll-like receptors 3, 7, and 9, in macrophages Biochemical and Biophysical Research Communications 458(1):28-33
  6. Sakuma C, Sato M, Takenouchi T, Kitani H (2015) Specific binding of the WASP N-terminal domain to Btk is critical for TLR2 signaling in macrophages Molecular Immunology 63(2):328-336
  7. Shinkai H, Matsumoto T, Toki D, Okumura N, Terada K, Uenishi H (2015) Porcine NOD1 polymorphisms with impaired ligand recognition and their distribution in pig populations Molecular Immunology 63(2):305-311
  8. Takenouchi T, Sekiyama K, Tsukimoto M, Iwamaru Y, Fujita M, Sugama S, Kitani H, Hashimoto M (2015) Role of autophagy in P2X7 receptor-mediated maturation and unconventional secretion of IL-1β in microglia Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging 6(14):211-222
  9. Toki Y, Takenouchi T, Harada H, Tanuma S, Kitani H, Kojima S, Tsukimoto M (2015) Extracellular ATP induces P2X7 receptor activation in mouse Kupffer cells, leading to release of IL-1β, HMGB1, and PGE2, decreased MHC class I expression and necrotic cell death Biochemical and Biophysical Research Communications 458(4):771-776
  10. Aoki S, Takezawa T, Miyazaki-Oshikata A, Ikeda S, Nagase K, Koba S, Inoue T, Uchihashi K, Nishijima-Matsunobu A, Kakihara N, Hirayama H, Narisawa Y, Toda S (2014) Collagen vitrigel membrane: a powerful tool for skin regeneration Inflammation and Regeneration 34(3):117-123
  11. Ishimaru M, Yusuke N, Tsukimoto M, Harada H, Takenouchi T, Kitani H, Kojima S (2014) Purinergic signaling via P2Y receptors up-mediates IL-6 production by liver macrophages/Kupffer cells The Journal of Toxicological Sciences 39(3):413-423
  12. Kitani H, Sakuma C, Takenouchi T, Sato M, Yoshioka M, Yamanaka N (2014) Establishment of c-myc-immortalized Kupffer cell line from a C57BL/6 mouse strain Results in Immunology 4:68-74
  13. Morozumi T, Iseki H, Toki D, Takagi M, Tsunemitsu H, Uenishi H (2014) Concise and broadly applicable method for determining the genomic sequences of North-American-type porcine reproductive and respiratory syndrome viruses in various clusters Journal of Veterinary Medical Science 76(9):1249-1255
  14. Sekiyama K, Waragai M, Akatsu H, Sugama S, Takenouchi T, Takamatsu Y, Fujita M, Sekigawa A, Rockenstein E, Inoue S, La Spada A.R, Masliah E, Hashimoto M (2014) Disease modifying effect of adiponectin in model of α-synucleinopathies Annals of Clinical and Translational Neurology 1(7):479-489
  15. Takenouchi T, Suzuki S, Shinkai H, Tsukimoto M, Sato M, Uenishi H, Kitani H (2014) Extracellular ATP does not induce P2X7 receptor-dependent responses in cultured renal- and liver-derived swine macrophages Results in Immunology 4:62-67
  16. Takenouchi T, Tsukimoto M, Hashimoto M, Kitani H (2014) Inflammasome activation by danger signals: extracellular ATP and pH Inflammasome 1(1):76-80
  17. Yoshida J, Oshikata A, Yokoo S, Yamagami S, Takezawa T, Amano S (2014) Development and evaluation of porcine atelocollagen vitrigel membrane with a spherical curve and transplantable artificial corneal endothelial grafts Investigative Ophthalmology & Visual Science 55(8):4975-4981 (DOI:10.1167/iovs.14-14211)
  18. Sato M, Sawahata R, Sakuma C, Takenouchi T, Kitani H (2013) Single domain intrabodies against WASP inhibit TCR-induced immune responses in transgenic mice T cells Scientific Reports 3:3003
  19. Tani A, Tada Y, Takezawa T, Wada I, Imaizumi M, Nomoto Y, Nomoto M, Omori K (2013) Regenerative process of tracheal epithelium using a collagen vitrigel sponge scaffold The Laryngoscope 123(6):1469-1473
  20. Yamaguchi H, Kojima H, Takezawa T (2013) Vitrigel-eye irritancy test method using HCE-T cells Toxicological Sciences (Advance Access) DOI: 10.1093/toxsci/kft159